What are the available treatments?
Glioblastoma is the most common and aggressive primary brain tumour in adults. Although it’s considered a rare cancer. Glioblastoma, also known as glioblastoma multiforme (GBM), that begins within the brain. Initially, signs and symptoms of glioblastoma are nonspecific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke
Please see the available treatments below:
- Brain Surgery
- Target Therapy
- Convection-enhanced delivery
- Electric field therapy
- Wafer therapy
- Nanoparticle therapy
- CBD Oil
Surgery is the first treatment. The surgeon tries to remove as much of the tumour as possible. In high-risk areas of the brain, it may not be possible to remove all of it. therefore causing the end points to grow into individual tumours. Talk to your consultant about the dangers of not removing the whole tumour. There is always going to be micro cells that will multiply, ask for comparable statistics for and against having surgery.
Chemotherapy. Temozolomide is the most common chemotherapy drug doctors use for glioblastoma. Carmustine (BCNU) and lomustine (CCNU) . Ask your oncology specialists about the effectiveness of Glioblastoma. Chemotherapy is normally used in-conjunction with Radiotherapy, Temozolomide causes the tumour to become sensitive, whilst the radiotherapy attack the cancer cells. You also take anti sickness tablets alongside Temozolomide called Ondansetron 4mg (Domperidone 10mg are not so effective) Normally they are taken 1 hour apart, to control the sickness take the Anti sickness tablet at 4am, Then the Chemotherapy at 5am, Then the Steroids at 6am and Breakfast at 7am.
Radiation is used to kill as many leftover tumour cells as possible after surgery. It can also slow the growth of tumours that can't be removed by surgery. It is also known to aggravate and swell the endpoints of the tumour, ask your Oncology specialists the benefits and downfalls of having radiation. Ask for a comparison.
Targeted therapy with the drug bevacizumab (Avastin, Mvasi) may be given if chemotherapy has not been effective.
Convection-enhanced delivery (CED) uses a pump to release a slow, continuous stream of chemotherapy or targeted therapies to a tumour.
Electric field therapy uses electrical fields to target cells in the tumor while not hurting normal cells. To do this, doctors put electrodes directly on the scalp. The device is called Optune. You get it with chemotherapy after surgery and radiation. The FDA has approved it for both newly diagnosed people and people whose glioblastoma has come back.
Wafer therapy (Gliadel) uses an implanted, biodegradable disc that releases chemotherapy to any cancerous tissue that is left after surgery.
Nanoparticle therapy uses tiny particles to carry chemotherapy directly into the tumor. At major cancer centers, you may also be able to get experimental treatments or oral chemotherapy, which you take at home. These treatments may help with symptoms and possibly put the cancer into remission in some people. In remission, symptoms may let up or disappear for a time.
Immunotherapy or Biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as activation immunotherapies, while immunotherapies that reduce or suppress are classified as suppression immunotherapies.
CBD oil is different from cannabis oil, because it does not contain THC. It is currently legal in the UK - as long as it has been produced from an EU approved strain of hemp and as long as it is marketed as a food supplement without any medicinal claims. You can buy it in many high street health food shops.